Ryan LaMarre accounted for all four runs for the Chicago White Sox, as the New York Yankees series finale 4-1.
With the loss, the Yankees dropped two out of three to the White Sox.
C.C Sabathia got the loss despite having a quality start. Sabathia pitched six innings while allowing three runs and struck out six.
Ronald Torreyes drove in the only run of the game for the Yankees.
The Yankees will look to bounce back tomorrow night as they start a four game series with the Detroit Tigers.